CLINICIAN > THE SECURITY OF ZIRTI SURFACE
The ideal implant surface should have the potential and capacity to act as a new niche for the mesenchymal precursors, which go to replace the marrow. The ace in the hole of the contemporary approach to implant surfaces and materials is understanding the factors that make up this niche, the knowledge of the stimuli that they can give to the cells, particularly to the cell precursors that are capable of differentiating themselves in mature bone cells: real tissue engineering capable of optimising the bone responses and maximise the integration of the implant in its tissue context.
Prof. Guido Maria Macaluso – Università di Parma
THE IMPLANT SURFACE: AN ALTERNATIVE NICHE
Introduction of Scientifica vol.I, - January 2011
The security of ZirTi surface
ZirTi is born from the awareness of the importance of the physical-chemical characteristics of the surface in contact with the bone. It is obtained through a sand-blasting process with zirconium oxide, followed by acid-etching, techniques that contribute to a topography to which the osteoblasts have shown to intimately adapt and to activate rapid proliferation.
With its roughness of 1.3-1.7 μm, it fits perfectly with the parameters defined by the 2nd Consensus Conference of the EAO (COIR, Vol. 20, Supp 4, September 2009) to obtain an excellent BIC.
Magnifications of primary osteoblasts on ZirTi surface: thanks to a section obtained with FIB (Focused Ion Beam), the intimate adaptation of one cell onto the characteristic peaks of the ZirTi surface is evident.
Image courtesy of Prof. G. M. Macaluso, University of Parma, Medicine and surgical department -
Dentistry center
Over the years, a series of scientific studies on ZirTi has shown that the surface, thanks to its chemical and morphological characteristics, is able to positively condition and modulate the cellular response, influencing the replicative capacity and differentiation potential. Ultimately, ZirTi favors the formation of bone tissue, an essential condition for achieving integration and, therefore, implant success.
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