CLÍNICOS > SUPERFICIE ZIRTI

La superficie ideal del implante debería tener todas las características para convertirse en el nuevo nicho para los precursores mesenquimales, sustituyendo el medular.  La comprensión de los factores que componen este nicho, el conocimiento de los estímulos que aquel consigue conferir a las células, en particular, a los precursores celulares capaces de diferenciarse en células óseas maduras es la base del enfoque contemporáneo hacia las superficies y los materiales del implante: una verdadera ingeniería del tejido capaz de optimizar las respuestas óseas y maximizar la integración del implante en su contexto.

Prof. Guido Maria Macaluso – Universidad de Parma

LA SUPERFICIE DEL IMPLANTE: UN NICHO SUSTITUTIVO

Introducción a Scientifica vol.I -enero de 2011

La seguridad de la superficie ZirTi

La seguridad de la superficie ZirTi

De la conciencia de la importancia de las características físico-químicas de la superficie en contacto con el hueso nace la ZirTi, que se ha obtenido a través de un proceso de arenado con óxido de zirconio seguido por un proceso de grabado. Estos procesos confieren a la superficie una topografía a los que los osteoblastos han demostrado adaptarse de manera íntima y en la que proliferan rápidamente.

 

La ZirTi, con su rugosidad de 1.3-1.7 μm, encaja perfectamente en los parámetros definidos por la 2° Consensus Conference de EAO (COIR, Vol. 20, Sup 4, September 2009) para obtener un BIC excelente.

Ampliaciones de osteoblastos primarios en la superficie ZirTi: en las imágenes es posible ver la adaptación íntima de una célula en los picos que caracterizan la ZirTi, gracias a una sección obtenida con FIB (Focused Ion Beam).

 

Imagen cortesía del Dr. Macaluso, Universidad de Parma, Departamento de Medicina y Cirugía - Centro de Odontología

En los años una serie de trabajos científicos sobre la ZirTi ha ido demostrando que esta superficie, gracias a sus características químicas y morfológicas peculiares, consigue condicionar y modular de manera positiva la capacidad replicadora y el potencial de diferenciación. En suma, la superficie ZirTi favorece la formación de tejido óseo, una condición irrenunciable para obtener la integración y, por lo tanto, el éxito del implante.

BIBLIOGRAFÍA:

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